Decisions about the medical treatment of children,until very recently, were based on the outcome of research conducted almost exclusively in adults.
The aim of this blog post is to lay emphasis on the essentiality of implementing pediatric study in clinical rotations.
This involves clinical trials (CTs) in compliance with the principles of effectivepediatric practice ꟷ be it with acute or chronic health conditions.
Let’s talk about the challenges that researches had to overcome to implement pediatric study in clinical rotations
First up, regarding the mechanism of metabolismand action.
This primarily includes the differences in treatment effects between young and adult patients.
For this, clinical trials were needed to adequately evaluate the effects of newly discovered medicines in children.
Some of the roadblocks that came across include:
- Lag in implementation of rules, especially with regard to ethical considerations, for the conduct of paediatric CTs;
- Theslack in developing an adequate methodology, while taking into account the pediatric specificitiesthat could enableresearchers to provide powered pieces of evidence;
- A gap in the economic interest of the pharmaceutical developers, due to the limited market offered by children.
Truly glad that these issues no longer persist!
So, how exactly does pediatric study help advance clinical medicine?
- Pediatric trial regulatory features
Thechanging rules on pediatric trials are making a direct impact on the recently approved CT regulations.
This mainly deals withꟷ trial authorization, assent and consent from parents and children,competencies and rules of Ethics Committees, and finally children confidentialityandprivacy.
- Pediatric plans and trials methods
Modern drug development approaches take into consideration the requirements of the pediatric population.
In particular, research is conducted in the following issues ꟷRandomized Controlled Trials (RCTs), validation ofpediatric endpoint and placebo use.
- Pediatric trial incentives and requirementsof the existing legislation
The U.S. legislation,by many years,has provideda series of financial incentives to study children’s medicine.
This has led to further stimulation of pediatric drug development.
Thanks to the significant increase in the number of pediatric trials being conducted.
Okay, so if you are an aspiring medical student, whose heart lies in pediatric treatment, I have some really good news for you!
Government across the globe have adoptedeffective measures to promote the conduct pediatric trials.
This paves for prospective candidates like you to get your hands into research right after earning your medical degree!
Today, the world is calling for sound scientific shreds of evidence for treatment benefits in adolescentsandchildren.
The conduct of CTs testing medications for their use in adolescents and children has become mandatory in almost all continents!
For quite some time now, the core activities performed at regulatory and scientific levels have managed to cover the preformed gaps in pediatric clinical medicine.
Clinical Medical programs offered in the Caribbean are designed to identify innovative methods of research to overcome the existing limitations related to pediatric medicine.
Care to be part of it?
Browse our website and crush that apply button to make your professional life much more rewarding!